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Key Scientific Terms

ACE (angiotension-converting enzyme) Inhibitor: A drug that lowers blood pressure by interfering with the breakdown of a protein-like substance involved in blood pressure regulation.

Angina pectoris: Chest pain that occurs when diseased blood vessels restrict blood flow to the heart.

Angioplasty: A non-surgical technique for opening partially closed or blocked arteries by temporarily inflating a tiny balloon inside the artery

Artery: A vessel that carries oxygen-rich blood from the heart to the body.

Arthroscopy: A surgical technique whereby a tube-like instrument is inserted into a joint to inspect, diagnose and repair tissues.

Beta blocker: A drug that lowers blood pressure by limiting the action of adrenaline (epinephrine), a hormone that increases blood pressure.

Diuretic: A drug that lowers blood pressure by stimulating fluid loss and promoting the production of urine.

Heart attack : Death of, or damage to, a region of heart muscle due to an insufficient blood supply.

Congestive heart failure (CHF): A condition in which the heart cannot pump all the blood returning to it, leading to a back-up of blood in vessels and accumulation of fluid in body tissues, including the lungs.

Coronary artery disease (CAD): A narrowing of the inside diameter of arteries that supply the heart with blood which interferes with the blood supply to the heart muscle. .

Good manufacturing process (GMP): Extensive quality assurance, accountability, and sterile conditions required for production of drugs for human usage.

Graft: Healthy skin, bone, or other tissue taken from one part of the body to replace diseased or injured tissue removed from another part of the body.

Infarction: Heart attack.

Mesenchymal stem cells (MSCs): Cells found in the bone marrow of adults, capable of differentiating into heart muscle, neurons, bone cells and other organ tissues.

Mesenchymal precursor cells (MPCs): Cells capable of giving rise to MSCs. They are primarily found in the bone marrow, dental pulp, fat and skin.

Monoclonal antibody: An antibody which specifically binds to the compound of interest.

Myocardial regeneration: The ability of heart muscle cells to divide and extend into the damaged region of the heart in a finger-like fashion. Angioblast has discovered that this process is dependent on sufficient oxygen and nutrients.

Ulcer: A region of damage to skin or an internal mucous surface that results in death of the tissue.